Weakly antiferromagnetic vanillin and acetate bridged dinuclear Ni(II) compound exhibiting catecholase-like activity and biological properties

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dc.contributor.authorVernekar, Beena K.
dc.contributor.authorHarmalkar, Nikita N.
dc.contributor.authorGaonkar, Sanket K.
dc.contributor.authorSannigrahi, Jhuma
dc.contributor.authorDhuri, Sunder N.
dc.date.accessioned2024-12-30T10:05:03Z
dc.date.available2024-12-30T10:05:03Z
dc.date.issued2024
dc.description.abstractA dinuclear nickel compound that features vanillin (van) and acetate (OAc) bridging ligands, [Ni sub(2)(Mu-van) sub(2)(Mu-OAc)(NCS) sub(3)(H sub(2)O)].5H sub(2)O 1, was synthesized and characterized using various techniques. Crystal structure analysis revealed a pair of Ni(II) ions bridged by an acetate anion through a Mu sub(2)-Eta sup(1):Eta sup(1) coordination mode. At the same time, vanillin bridges both nickel(II) centers through phenolic oxygen, separating the two Ni ions by a distance of 3.001(7) angstrom. The temperature-dependent magnetism indicates weak antiferromagnetic behaviour in compound 1, following the Curie-Weiss law with Curie constant C = 1.0145 cm sup(3) K mol sup(-1) and Weiss constant Theta = -4.1 K. Compound 1 was evaluated for its ability to mimic the catechol oxidase enzyme using 3,5-di-tert-butylcatechol as a model substrate with a K sub(cat) value of 157.1 x 102 h sup(-1). Furthermore, compound 1 was tested for its cytotoxicity against HepG2 cancer cells and DNA cleavage properties.
dc.identifier.citationNew Journal of Chemistry. 48(8); 2024; 3472-3482.
dc.identifier.issn1144-0546
dc.identifier.urihttps://doi.org/10.1039/D3NJ04662A
dc.identifier.urihttp://khandolacollege.ndl.gov.in/handle/123456789/135
dc.language.isoen
dc.publisherRoyal Society of Chemistry
dc.subjectNATURAL SCIENCES::Chemistry
dc.titleWeakly antiferromagnetic vanillin and acetate bridged dinuclear Ni(II) compound exhibiting catecholase-like activity and biological properties
dc.typeArticle
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