Browsing by Author "Prabhugaonkar, Arya"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Mycosynthesized magnetite particles:Comparative physicochemical properties and antifungal activity
    (Elsevier, 2026) Prabhugaonkar, Arya; Mordekar, Rajashri Karmali
    The study focuses on antifungal applications of Fe3O4 synthesized by Chemical and fungal methods. Fe3O4 is synthesized by conventional hydroxide method and mycosynthesized using fungi G. lucidum and P. rimosus. The Fe3O4 synthesized by all three methods is Pure, crystalline and magnetic. Fe3O4 synthesized by fungal methods show fine crystallite size and agglomeration than the one synthesized by chemical method. There is evidence of phenolic and amino groups which are indicative of phytochemicals in mycosynthesized Fe3O4. All synthesized samples are good antifungal agents against pathogenic fungi C. albicans and A. flavus with sensitivity in the range of 500 to 7.81 μg/mL. Fe3O4 synthesized using P. rimosus (P– Fe3O4) shows better sensitivity (S) at concentrations from 500 to 4.0 μg/ml for pathogens C. albicans and A. flavus in comparison to G- Fe3O4 and C– Fe3O4. The materials show sensitivity superior to some of the reported composites of magnetite with noble metals and Schiff bases like Fe3O4@Ag, Fe3O4@SiO2/Schiff Base/Cu(II)MNPS These potential antifungal agents being magnetic, can be used synergistically with antifungal drugs which will facilitate their movement within the target tissue by means of external magnetic field. This will also minimize the dosage and toxicity of the antifungal drugs.