Browsing by Author "Albuquerque, Marina"

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    Impact Of Agrochemicals On Global Climate Change & Sustainable Human Health
    (Veterinary Organization, 2024) Tambe, Deepmala Babasaheb; Hemavathi, B.; Anuradha, S.; Siddulu, N.; Albuquerque, Marina; Parshaveni, Balaraju; Patil, Devidas Narhar
    The application of agrochemicals represents a wide range of chemical entities applied in agriculture toward enhancing crop production and pest control. This has important implications for both global climate change and human health sustainability. Article focusing on exploring the impact of some bioactive compounds derived from endophytic fungi metabolites, viewing their potential as being antioxidants, antifungals, antibacterials, and anticancer agents. Endophytic fungi are fungi that reside within plant tissue but do not cause damage, while it is their metabolites, notably alkaloids, terpenes, quinolones, and other secondary metabolites, which present an array of biological activities for agricultural and pharmaceutical applications. Extractive methods include those techniques that identify metabolites either from fungal cultures or plants that have endophytes, succeeded by purification to obtain compounds at high purity levels for further studies and applications. Characterization methods describe the chemical structures and properties of those compounds of importance in understanding their bioactivities and potential uses; among these are the spectroscopic techniques of NMR and mass spectrometry, which describe. The paper seeks to discuss the dual roles of agrochemicals in relation to environmental dynamics and human welfare. On the one hand, potential benefits to agriculture could include increased productivity, security of food availability, and economic growth. On the other, concern exists over far-reaching environmental pollution, disruption of ecosystems, and exposure of humans to residues, which pose health threats. Against the background of emerging climatic challenges stands the imperativeness of knowledge on the sustainable use of agrochemicals. With respect to agriculture, the reduced use of synthetic chemicals through the exploitation of endophytic fungal bioactives looks forward to reduce environmental impacts, improving human health with safer alternatives
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    Role of Probiotic Bacteria and Yeast in Tackling ADHD And ASD
    (Ibadan Biomedical Communications Group, 2024) Gangwar, S.P.; Madhu; Albuquerque, Marina; Deshmukh, Madhuri V.
    Attention-Deficit/Hyperactivity Disorder (ADHD) and autism spectrum disorder (ASD) are neurodevelopmental conditions with complex etiologies involving both genetic and environmental factors. Emerging research highlights the critical role of the gut-brain axis in their pathophysiology, positioning probiotics as potential therapeutic agents. Probiotic bacteria such as Lactobacillus and Bifidobacterium and yeast like Saccharomyces boulardii have shown promise in modulating gut microbiota, reducing neuroinflammation, and influencing neurotransmitter production. This chapter explores the mechanisms through which probiotics impact ADHD and ASD, examines clinical evidence, and addresses the challenges and future directions for their use in managing these conditions. Probiotics represent a novel and integrative approach that could complement existing therapeutic strategies, offering hope for improved outcomes in affected individuals.